1781–1782
1781–1782 Primera de las cinco grandes pandemias de gripe previas a la de 1918 (Volver a Cronología. Personas. Fuentes.)
Pandemic evolved so rapidly, and was so widespread, that explosive outbreaks of febrile respiratory illness in the general population alone became a distinguishing characteristic, supporting the notion of a specific disease entity.
(Volver a Cronología. Personas. Fuentes.)